Non-selective beta-blockers are not associated with serious infections in veterans with cirrhosis
نویسندگان
چکیده
منابع مشابه
Proton pump inhibitors are associated with a high rate of serious infections in veterans with decompensated cirrhosis.
BACKGROUND There is increasing evidence that proton pump inhibitors (PPIs) increase the rate of infections in patients with decompensated cirrhosis. AIMS To estimate the extent to which proton pump inhibitors (PPIs) increase the rate of infections among patients with decompensated cirrhosis. METHODS We conducted a retrospective propensity-matched new user design using US Veterans Health Adm...
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Since the original description of the effectiveness of β-blockers in lowering the portal pressure and therefore the risk of variceal bleeding, more than 500 articles in the English literature on the use of non selective β-blockers (NSBB) in cirrhosis have been published. The use of NSBB in pre-primary prophylaxis of variceal bleeding is currently not indicated. In primary prophylaxis, patients ...
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For over 30 years, nonselective beta-blockers (NSBB) have been successfully used for preventing variceal bleeding in patients with cirrhosis and portal hypertension. Nevertheless, recent studies suggest that NSBB may be effective only within a particular "therapeutic window" in patients with advanced liver disease. Outside of this window, in early stages of cirrhosis and in very advanced cirrho...
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BACKGROUND Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown. METHODS We randomly assigned 213 patients with cirrhosis and portal hypertension (minimal hepatic venous pressure gradient [HVPG] of 6 mm Hg) to receive timolol, a nonselective beta-blocker (108 patients), or placebo (105 patients). T...
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President, Staff Society N. A. Kshirsagar Editor Atul Goel Associate Editors Sandeep Bavdekar Lakshmi Rajgopal Consulting Editors Nithya Gogtay Sanjay Mehta Vinita Salvi Managing Editor D. K. Sahu Members Amita Athavale Abhay Dalvi Sucheta Dandekar Hemant Deshmukh Anil Patwardhan Preeti Mehta Nalini Shah Lalita Tuteja Pradeep Vaideeswar S. V. Vaidya Editorial Assistants Shilpa Abhyanakar Jignes...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2013
ISSN: 0269-2813
DOI: 10.1111/apt.12382